PLEASE!!! Do not give your dog ANY medication until you talk to a Vet and ask them!! Some medications that humans take for allergies, like Benadryl, are safe for dogs, but the dosage is way different and unless the person that you talk to on here is a Veternarian, or an Vet Tech. they really don't know the exact dose to give your dog! Some formulations may use a concentration of 6.25 mg per 5 mL, which means you will have to use twice as much as normal. Topical: Benadryl is also available in the form of cream, gel, stick, or spray, usually containing 1% diphenhydramine (or 2% in the extra strength formula), which can be applied topically 2 – 3 times daily. Benadryl Dosage for Dogs – How Much Should You Give a Dog? Before using any dosage guidelines, make sure you check with your vet, as there is a range of circumstances that might change the amount you should administer. By continuing to use this site you consent to the use of cookies on your device as described in our cookie policy unless you have disabled them. By continuing to use this site you consent to the use of cookies on your device as described in our cookie policy unless you have disabled them. If your dog is suffering from allergies, you may be wondering if you can give your pet Benadryl. Find out on petMD. They aren't the exact same, but very close. Benadryl is diphenhydramine (bonded in a hydrochloride salt formulation). Dramamine is also diphenhydramine, but bonded to 8-chlorotheophylline, which whoever put the two together decided to give a different name altogether: dimenhydrinate. FINDING THE CORRECT BENADRYL DOSAGE FOR DOGS. The usual dose of Benadryl for dogs (adult) is 2 to 4 milligrams per kilogram of body weight, which corresponds to a dose of 0.9 to 1.8 miligrams per pound of body weight, according to the Merck Veterinary Manual. 2. Honest Paws Restore CBD Dog Treats. Honest Paws makes the absolute best CBD dog treats, and better yet, it has a treat pack formulated specifically for allergic dogs called the ‘RESTORE’. Always consider a professional before giving your dog Benadryl. You can use this table as an instrument to see how much Benadryl (Diphenhydramine) you can give your dog.